Project book

Lonvi Bio — PCC1 Senolytic Platform

Longevity & Biotechnology · Global · United States

Project website

Target size

US$20M

Subscribed

US$6M

Target IRR

22%

Horizon

5 yrs

Risk

High

Status

Open

Investment case

Procyanidin C1 (PCC1) is the polyphenol most strongly linked in current literature to clearing senescent — or "zombie" — cells, the aged cells that drive chronic systemic inflammation and biological ageing. Standard grape-seed and apple extracts contain only 0.1–0.6% PCC1 and are poorly absorbed.

Lonvi has pioneered an extraction method that concentrates active PCC1 to roughly 20%, and engineered a phytosomal delivery shield that improves absorption several-fold, while driving extraction cost down by over 95%. A single three-day regimen is presented as the PCC1 equivalent of three metric tons of grapes. Early pre-clinical human work reported 25–75% reductions in SASP inflammatory markers and senescent markers such as IL-6, IL-8, p21 and SA-β-gal; results remain under peer review.

Revenue comes from a consumer senolytic protocol plus research reagents — senescent cell detection kits and senolytic and senomorphic compound libraries sold to laboratories.

Highlights

  • PCC1 concentrated to roughly 20% — around 30x standard grape-seed extract
  • Phytosomal delivery engineered for materially higher absorption
  • Early pre-clinical human data: 25–75% reductions in IL-6, IL-8 and p21
  • Two revenue lines: consumer protocol and laboratory research reagents
  • Extraction cost reduced by over 95% versus traditional methods

Allocation

Open

US$100K

Minimum commitment

US$6M subscribed32%

of US$20M target

Target IRR
22%
Horizon
5 years
Risk rating
High
Structure
Closed-ended, USD

Indicative terms. Allocation is subject to eligibility, documentation and availability.