Lonvi Bio — PCC1 Senolytic Platform
Longevity & Biotechnology · Global · United States
Project websiteTarget size
US$20M
Subscribed
US$6M
Target IRR
22%
Horizon
5 yrs
Risk
High
Status
Open
Investment case
Procyanidin C1 (PCC1) is the polyphenol most strongly linked in current literature to clearing senescent — or "zombie" — cells, the aged cells that drive chronic systemic inflammation and biological ageing. Standard grape-seed and apple extracts contain only 0.1–0.6% PCC1 and are poorly absorbed.
Lonvi has pioneered an extraction method that concentrates active PCC1 to roughly 20%, and engineered a phytosomal delivery shield that improves absorption several-fold, while driving extraction cost down by over 95%. A single three-day regimen is presented as the PCC1 equivalent of three metric tons of grapes. Early pre-clinical human work reported 25–75% reductions in SASP inflammatory markers and senescent markers such as IL-6, IL-8, p21 and SA-β-gal; results remain under peer review.
Revenue comes from a consumer senolytic protocol plus research reagents — senescent cell detection kits and senolytic and senomorphic compound libraries sold to laboratories.
Highlights
- PCC1 concentrated to roughly 20% — around 30x standard grape-seed extract
- Phytosomal delivery engineered for materially higher absorption
- Early pre-clinical human data: 25–75% reductions in IL-6, IL-8 and p21
- Two revenue lines: consumer protocol and laboratory research reagents
- Extraction cost reduced by over 95% versus traditional methods
Allocation
OpenUS$100K
Minimum commitment
of US$20M target
- Target IRR
- 22%
- Horizon
- 5 years
- Risk rating
- High
- Structure
- Closed-ended, USD
Indicative terms. Allocation is subject to eligibility, documentation and availability.
